PRESS & PUBLICATIONS

All the publications below acknowledge ENGAGE funding. ENGAGE-led publications are highlighted.

2010

Milani L and al. DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia. Blood. 2010 Feb 11;115(6):1214-25. Epub 2009 Nov 25.

Saxena R and al. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet. 2010 Feb;42(2):142-8. Epub 2010 Jan 17.

Codd V and al. Common variants near TERC are associated with mean telomere length. Nat Genet. 2010 Mar;42(3):197-9. Epub 2010 Feb 7.

Dupuis J et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010 Jan 17.

Illig T and al. A genome-wide perspective of genetic variation in human metabolism. Nat Genet. 2010 Feb;42(2):137-41. Epub 2009 Dec 27.

Repapi Eet., al. Genome-wide association study identifies five loci associated with lung function. Nat Genet. 2010 Jan;42(1):36-44. Epub 2009 Dec 13. PubMed PMID: 20010834.

2009

Soranzo et al. A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nature Genetics 41(11), 1182- 90 (2009). Published online: 11 October 2009

Chambers et al. Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Nature Genetics 41(11), 1161-2 (2009). Published online: 11 October 2009

Krestyaninova M and al. A System for Information Management in BioMedical Studies--SIMBioMS. Bioinformatics. 2009 Oct 15;25(20):2768-9. Epub 2009 Jul 24.

Jonsson A and al. A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion. Diabetes. 2009 Oct;58(10):2409-13. Epub 2009 Jul 7.

Kolz et al. Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations. PLoS Genet. 2009 Jun;5(6):e1000504. Epub 2009 Jun 5.

Grisoni ML and al. Lack of association between polymorphisms of the IL18R1 and IL18RAP genes and cardiovascular risk: the MORGAM Project. BMC Med Genet. 2009 May 27;10:44.

Saarela O, Kulathinal S, Karvanen J. Joint analysis of prevalence and incidence data using conditional likelihood. Biostatistics. 2009 Jul;10(3):575-87. Epub 2009 May 20.

Iris M. Heid et al., Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design? Plos Gen 2009;5:e1000694

Mari Nelis, Tõnu Esko, et al. Genetic Structure of Europeans: a view from the North-East. PLoS ONE 4(5): e5472

Sovio U and al. Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966. PLoS Genet. 2009 Mar;5(3):e1000409. Epub 2009 Mar 6.

Bartha Maria Knoppers. Genomics and policymaking: from static models to complex systems? Human Genetics 2009 May;125(4):375-9. Epub 2009 Feb 28

Pulizzi N and al. Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes. Diabetologia. 2009 May;52(5):825-9. Epub 2009 Feb 19.

Coronary Artery Disease Consortium. Large scale association analysis of novel genetic loci for coronary artery disease. Arterioscler Thromb Vasc Biol. 2009 May;29(5):774-80. Epub 2009 Jan 22.

Erdmann J and al. New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet. 2009 Mar;41(3):280-2. Epub 2009 Feb 8.

2008

Inga Prokopenko et al. Variants in MTNR1B fasting glucose levels. Nature Genetics 41, 77 - 81 (2008) Published online: 7 December 2008 | doi:10.1038/ng.290

Gudmar Thorleifsson et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nature Genetics 41, 18 - 24 (2008). Published online: 14 December 2008

Saarela O and al. Nested case-control data utilized for multiple outcomes: a likelihood approach and alternatives. Stat Med. 2008 Dec 10;27(28):5991-6008.

Aulchenko, Ripatti et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nature Genetics 41, 47 - 55 (2008) Published online: 7 December 2008

Sabatti et al. Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nature Genetics 41, 35 - 46 (2008). Published online: 7 December 2008

Cristen J Willer et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genetics 41, 25 - 34 (2008). Published online: 14 December 2008

Valeriya Lyssenko et al. Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nature Genetics 41, 82 - 88 (2008) Published online: 7 December 2008

Grisoni M-L et al. Haplotypic analysis of tag SNPs of the interleukin-18 gene in relation to cardiovascular disease events: the MORGAM Project. European Journal of Human Genetics. 2008 Dec;16(12):1512-20. Epub 2008 Jul 16.

Karvanen et al. The impact of newly identified loci on coronary heart disease, stroke and total mortality in the MORGAM prospective cohorts. Genet Epidemiol. 2009;33:237-246.