Clinical Translation (WP7)

WP7 is designed to accelerate the translation of the findings into the clinical arena. It will build on the basic research findings of the previous WPs, but will provide additional insights into the physiological and pharmacogenomic ramifications. It will use the epidemiological findings of WP7 to explore the potential for the development of diagnostics, and data from prospective and cross-sectional cohorts to understand how genetic information can productively be combined with genomic (‘biomarker’) data to provide more precise diagnostic and prognostic tools. WP7 will also aim to understand how a molecular classification of disease can be used to improve the use of existing therapeutic agents. WP7 will concerned with the dissemination of findings to relevant biotech and pharma entities (including some within ENGAGE, and others without) to ensure speedy transition, where appropriate, into the development of clinical diagnostics, and novel therapeutics.